diff --git a/tests/e2e/offline_inference/test_moss_tts_nano_expansion.py b/tests/e2e/offline_inference/test_moss_tts_nano_expansion.py
index 2763adf4f..0cc8deea2 100644
--- a/tests/e2e/offline_inference/test_moss_tts_nano_expansion.py
+++ b/tests/e2e/offline_inference/test_moss_tts_nano_expansion.py
@@ -32,6 +32,7 @@ _OMNI_RUNNER_PARAM = (
 )
 
 pytestmark = [
+    pytest.mark.skip(reason="issue#4361"),
     pytest.mark.full_model,
     pytest.mark.tts,
     pytest.mark.parametrize("omni_runner", [_OMNI_RUNNER_PARAM], indirect=True),
diff --git a/tests/e2e/online_serving/test_moss_tts_nano_expansion.py b/tests/e2e/online_serving/test_moss_tts_nano_expansion.py
index d10dd6f57..66c0217a9 100644
--- a/tests/e2e/online_serving/test_moss_tts_nano_expansion.py
+++ b/tests/e2e/online_serving/test_moss_tts_nano_expansion.py
@@ -25,11 +25,11 @@ from tests.helpers.runtime import OmniServerParams
 from tests.helpers.stage_config import get_deploy_config_path
 
 # ``omni`` for all tests; 001/002 also get ``full_model`` via ``TestMossTtsNanoFull`` (003 is core+advanced only, no full_model).
-pytestmark = [pytest.mark.full_model, pytest.mark.tts]
-
-_SKIP_ISSUE_3168 = pytest.mark.skip(
-    reason="https://github.com/vllm-project/vllm-omni/issues/3168",
-)
+pytestmark = [
+    pytest.mark.skip(reason="issue#4361"),
+    pytest.mark.full_model,
+    pytest.mark.tts,
+]
 
 MODEL = "OpenMOSS-Team/MOSS-TTS-Nano"
 REF_AUDIO_URL = "https://raw.githubusercontent.com/OpenMOSS/MOSS-TTS-Nano/main/assets/audio/zh_1.wav"