diff --git a/tests/worker/test_worker_base.py b/tests/worker/test_worker_base.py
index 18131a31c..4570e6eda 100644
--- a/tests/worker/test_worker_base.py
+++ b/tests/worker/test_worker_base.py
@@ -239,3 +239,25 @@ def test_wake_up_forwards_tags_to_allocator(monkeypatch):
 
     assert OmniGPUWorkerBase.wake_up(worker, tags=["weights"]) is True
     assert calls["tags"] == ["weights"]
+
+
+def test_cuda_profiler_is_wired_for_omni_worker(monkeypatch):
+    import vllm.profiler.wrapper as profiler_wrapper
+
+    def fake_gpu_worker_init(worker, *args, **kwargs):
+        worker.vllm_config = SimpleNamespace(profiler_config=SimpleNamespace(profiler="cuda"))
+        worker.local_rank = 0
+        worker.rank = 0
+        worker.profiler = None
+
+    class FakeCudaProfiler:
+        def __init__(self, profiler_config):
+            self.profiler_config = profiler_config
+
+    monkeypatch.setattr(base.GPUWorker, "__init__", fake_gpu_worker_init)
+    monkeypatch.setattr(profiler_wrapper, "CudaProfilerWrapper", FakeCudaProfiler)
+
+    worker = OmniGPUWorkerBase()
+
+    assert isinstance(worker.profiler, FakeCudaProfiler)
+    assert worker.profiler.profiler_config.profiler == "cuda"
diff --git a/vllm_omni/worker/base.py b/vllm_omni/worker/base.py
index 2a7e9c876..01a08bd72 100644
--- a/vllm_omni/worker/base.py
+++ b/vllm_omni/worker/base.py
@@ -58,6 +58,13 @@ class OmniGPUWorkerBase(GPUWorker):
                 worker_name=worker_name,
                 local_rank=self.local_rank,
             )
+        elif profiler_config and profiler_config.profiler == "cuda":
+            # OmniGPUWorkerBase replaces vLLM's torch profiler above; keep the
+            # native CUDA profiler wrapper available for Nsight Systems capture
+            # through the /start_profile and /stop_profile endpoints as well.
+            from vllm.profiler.wrapper import CudaProfilerWrapper
+
+            self.profiler = CudaProfilerWrapper(profiler_config)
 
     def profile(self, is_start: bool = True, profile_prefix: str | None = None):
         """Override to set trace filename before starting the profiler.